Use Of Traditional Herbal Medicine, Content Compound Bioactives And Effects His Physiology Is On The Rise Immunity Body : Systematic Literature Review

Authors

  • Muslimah Muslimah Faculty of Medicine, Universitas Muhammdiyah Semarang, Indonesia
  • Che Wan Jasimah Bt Wan Mohamed Radzi Department of Science and Technology Studies, Faculty of Science, Universiti Malaya, Malaysia
  • Suyadi Suyadi Department of Science and Technology Studies, Faculty of Science, Universiti Malaya, Malaysia
  • Ari Yuniastuti Department of Biology, Faculty Mathematic and Natural Science, Universitas Negeri Semarang,Indonesia
  • Swasty Swasty Faculty of Medicine, Universitas Muhammdiyah Semarang, Indonesia
  • Nina Anggraeni Noviasari Faculty of Medicine, Universitas Muhammdiyah Semarang, Indonesia
  • Muhammad Sowwam Faculty of Medicine, Universitas Muhammdiyah Semarang, Indonesia
  • Qeyza Naufalia Riz Asmara Faculty of Medicine, Universitas Muhammdiyah Semarang, Indonesia

DOI:

https://doi.org/10.51601/ijse.v4i3.106

Abstract

Background: Combination trend​ treatment use herbal and conventional medicines, respectively gradually move going to approach integrative. Use herbal medicine is considered correlated more near with attitudes and beliefs public because can increase immunity body and eliminate worries effect side to drug pharmacy. This is also proven with various type disease that has resolved . Objective: Take inventory use commodity herbal plants and ingredients bioactive as well as study his physiology on the rise immune body. Method: Systematic literature review written based on the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines. Search done via ScienceDirect and Sage databases with use related keywords​​ with traditional herbal medicine, content compound bioactive and enhancement immunity body. Collecting data from a database involves keyword combination​ with Boolean operators. A total of 24 articles used as internal data this review study. Result: Various potential herbal medicine for utilized in a way massive including Divya- Swasari -Ras (DSR) with potential overcome asthma; Polygony multiflori For handle intestinal inflammation; Bu Shen Hui Yang Fang (BSHY) for overcome cancer blood leukemia; Skin wood is listed as anti-inflammatory; Ciji- Hua'ai - Baosheng (CHBD) decoction as antitumor; Sinisan For management of chronic hepatitis; Ganoderma lucidum as immunostimulator; Pudilan (PDL) as anti-SARS-COV-2; Carthamus tinctorius L.for handling cardiovascular; Lycium barbarum polysaccharide (LBP) as probiotics; Eucommia ulmoides Oliver as material diabetes medication; Stew Gubenfangxiao (GBFXD) as drug Respiratory; Naodesheng Tablets (NDS) as drug Alzheimer's disease; Astragalus membranaceus (Huangqi (HQ)) for uveitis treatment; Gun-Chil-Jung Capsules (GCJ) as anti cancer; Ligusticum Chuanxiong (Rhizoma chuanxiong) and Borneol ( Borneolum syntheticum) as drug atherosclerosis; Salvia miltiorrhiza Bge.as drug tumor at a time protector endothelium vascular; Tetrastigma hemsleyanum Diels et Gilg for handling injury lungs I; Achyranthis bidentatae For drug disease kidney; Acanthus ilicifolius L., Phyllodium pulchellum (L.) Desv .and Cudrania cochinchinensis Lour.as anti-hepatitis; Epimedium as an antitumor for melanoma, Punica granatum For treatment injury heart; Sanghuangporus sanghuang as anti-inflammatory protector network lungs; and Combretum micranthum as anti-inflammatory . Conclusion: Usage traditional herbal medicine effect on improvement system immune The body is supported by various compound bioactives in these herbal plants .

Downloads

Download data is not yet available.

References

Balkrishna, A.et al.(2020) 'Biomedicine & Pharmacotherapy Calcio-herbal formulation, Divya-Swasari-Ras, alleviates chronic inflammation and suppresses airway remodeling in mouse model of allergic asthma by modulating pro-in inflammatory cytokine response', Biomedicine & Pharmacotherapy, 126( February), p.110063.doi: 10.1016/j.biopha.2020.110063.

Bihonegn, T.et al.(2019) 'Antimalarial activity of hydromethanolic extract and its solvent fractions of Vernonia amygdalina leaves in mice infected with Plasmodium berghei', SAGE Open Medicine, 7.

Chen, G.et al.(2021) 'Microbiome analysis combined with targeted metabolomics reveals immunological anti-tumor activity of icariside I in a melanoma mouse model', Biomedicine and Pharmacotherapy, 140(January), p.111542.doi: 10.1016/j.biopha.2021.111542.

Chien, L.-H.et al.(2023) 'Evaluation of lung protection of Sanghuangporus sanghuang through TLR4/NF-κB/MAPK, keap1/Nrf2/HO-1, CaMKK/AMPK/Sirt1, and TGF-β/SMAD3 signaling pathways mediating apoptosis and autophagy', Biomedicine & Pharmacotherapy, 165, p.115080.doi: 10.1016/j.biopha.2023.115080.

Chien, L.H.et al.(2022) 'Study on the potential of Sanghuangporus sanghuang and its components as COVID-19 spike protein receptor binding domain inhibitors', Biomedicine and Pharmacotherapy, 153(July), p.113434.

Forhad, M.et al.(2020) 'Biomedicine & Pharmacotherapy Pharmacological insights and prediction of lead bioactive isolates of Dita bark through experimental and computer-aided mechanisms', Biomedicine & Pharmacotherapy, 131, p.110774.doi: 10.1016/j.biopha.2020.110774.

He, X.et al.(2021) 'Biomedicine & Pharmacotherapy component from Polygoni multiflori Radix (Heshouwu) suppresses DSS induced acute colitis in BALb/c mice by modulating gut microbiota', Biomedicine & Pharmacotherapy, 137(December 2020), p.111420.doi: 10.1016/j.biopha.2021.111420.

Huang, Q.et al.(2021) 'Systematic investigation of the pharmacological mechanism for renal protection by the leaves of Eucommia ulmoides Oliver using UPLC-Q-TOF/MS combined with network pharmacology analysis', Biomedicine and Pharmacotherapy, 140(May), p.111735.doi: 10.1016/j.biopha.2021.111735.

Jun, HJ et al.(2020) 'The Survival Benefit of Combination Therapy With Mild Temperature Hyperthermia and an Herbal Prescription of Gun-Chil-Jung in 54 Cancer Patients Treated With Chemotherapy or Radiation Therapy: A Retrospective Study', Integrative Cancer Therapies, 19.doi: 10.1177/ 1534735420926583.

Kong, Q.et al.(2020) 'Analysis of the molecular mechanism of Pudilan (PDL) treatment for COVID-19 by network pharmacology tools', Biomedicine and Pharmacotherapy, 128(May).

Kpemissi, M.et al.(2019) 'Nephroprotective activity of Combretum micranthum G.Don in cisplatin induced nephrotoxicity in rats: In-vitro, in-vivo and in-silico experiments', Biomedicine and Pharmacotherapy, 116(April), p.108961.doi: 10.1016/j.biopha.2019.108961.

Lei, W.et al.(2019) 'Phthalides, senkyunolide A and ligustilide, show immunomodulatory effect in improving atherosclerosis, through inhibiting AP-1 and NF-κB expression', Biomedicine and Pharmacotherapy, 117(May), p.109074.doi: 10.1016/j.biopha.2019.109074.

Li, Y.et al.(2021) 'Probiotic fermentation of Ganoderma lucidum fruiting body extract promoted its immunostimulatory activity in mice with dexamethasone-induced immunosuppression', Biomedicine and Pharmacotherapy, 141(July).doi: 10.1016/j.biopha.2021.111909.

Liao, L.Y., He, Y.F., Li, L., Meng, H., Dong, Y.M., Yi, F., & Xiao, P.G.(2018).A preliminary review of studies on adaptogens: Comparison of their bioactivity in TCM with that of ginseng-like herbs used worldwide Milen Georgiev, Ruibing Wang.Chinese Medicine (United Kingdom), 13 (1), 1–12.

Lu, J.et al.(2023) 'Network Pharmacology and Experimental Analyzes on Astragalus membranaceus (Huangqi) Effects on Endotoxin-induced Uveitis Model in Rats', Pharmacognosy Magazine, 19(3).

Rahayu, YYS, Araki, T., & Rosleine, D.(2020).Factors influencing the use of herbal medicines in the universal health coverage system in Indonesia.Journal of ethnopharmacology, 260, 112974.

Schwager, J.et al.(2018) 'Z-ligustilide and anti-inflammatory prostaglandins have common biological properties in macrophages and leukocytes', Nutrition and Metabolism, 15(1), pp.1–13.doi: 10.1186/s12986-018-0239-1.

Shu, Z.et al.(2018) 'Biomedicine & Pharmacotherapy Clarifying of the potential mechanism of Sinisan formula for treatment of chronic hepatitis by systems pharmacology method', 100(November 2017), pp.532–550.

Sumarni, W., Sudarmin, S., Sumarti, SS, & Kadarwati, S.(2022).Indigenous knowledge of Indonesian traditional medicines in science teaching and learning using a science–technology–engineering–mathematics (STEM) approach.Cultural Studies of Science Education, 1-44.

Sun, G.et al.(2021) 'Pharmacodynamic substances in Salvia miltiorrhiza for prevention and treatment of hyperlipidemia and coronary heart disease based on lipidomics technology and network pharmacology analysis', Biomedicine and Pharmacotherapy, 141.doi: 10.1016/j.biopha.2021.111846.

Wang, B.et al.(2022) 'Polysaccharides from Tetrastigma Hemsleyanum Diels et Gilg attenuate LPS-induced acute lung injury by modulating TLR4/COX-2/NF-κB signaling pathway', Biomedicine and Pharmacotherapy, 155(July), p.113755.doi: 10.1016/j.biopha.2022.113755.

Wang, S.et al.(2020) 'Raw and salt-processed Achyranthes bidentata attenuate LPS-induced acute kidney injury by inhibiting ROS and apoptosis via an estrogen-like pathway', Biomedicine and Pharmacotherapy, 129(March), p.110403.doi: 10.1016/j.biopha.2020.110403.

Wang, T.et al.(2018) 'Protective effects of Punica granatum (pomegranate) peel extract on concanavalin A-induced autoimmune hepatitis in mice', Biomedicine and Pharmacotherapy, 100(September 2017), pp.213–220.

Wang, Y.et al.(2021) 'Traditional Chinese medicine compound, Bu Sheng Hui Yang Fang, promotes the proliferation of lymphocytes in the immunosuppressed mice potentially by upregulating IL-4 signaling', Biomedicine and Pharmacotherapy, 134(December 2020), p.111107.doi: 10.1016/j.biopha.2020.111107.

Xi, S.et al.(2018) 'Biomedicine & Pharmacotherapy The effects of Ciji-Hua 'ai-Baosheng on immune function of mice with H 22 hepatocellular carcinoma receiving chemotherapy', Biomedicine & Pharmacotherapy, 101(4221), pp.898–909.doi: 10.1016/j.biopha.2018.03.027.

Xing, QQ et al.(2019) 'Serum proteomics analysis based on label-free revealed the protective effect of Chinese herbal formula Gu-Ben-Fang-Xiao', Biomedicine and Pharmacotherapy, 119(April), p.109390.

Yu, G.et al.(2019) 'Uncovering the pharmacological mechanism of Carthamus tinctorius L.on cardiovascular disease by a systems pharmacology approach', Biomedicine and Pharmacotherapy, 117(June), p.109094.

Zhang, B.et al.(2021) 'Effects of Naodesheng tablets on amyloid beta-induced dysfunction: A traditional Chinese herbal formula with novel therapeutic potential in Alzheimer's disease revealed by systems pharmacology', Biomedicine and Pharmacotherapy, 141.doi: 10.1016/j.biopha.2021.111916.

Zhao, Q.et al.(2022) 'The underlying mechanisms of anti-hepatitis B effects of Le-Cao-Shi formula and its single herbs by network pharmacology and gut microbiota analysis', Biomedicine and Pharmacotherapy, 148(January), p.112692.doi: 10.1016/j.biopha.2022.112692.

Zhu, W.et al.(2020) 'Prebiotic, immuno-stimulating and gut microbiota-modulating effects of Lycium barbarum polysaccharide', Biomedicine and Pharmacotherapy, 121(October 2019), p.109591.

Downloads

Published

2024-08-31

How to Cite

Muslimah, M., Wan Jasimah Bt Wan Mohamed Radzi, C. ., Suyadi, S., Yuniastuti, A. ., Swasty, S., Anggraeni Noviasari, N. ., Sowwam, M. ., & Naufalia Riz Asmara, Q. (2024). Use Of Traditional Herbal Medicine, Content Compound Bioactives And Effects His Physiology Is On The Rise Immunity Body : Systematic Literature Review. International Journal of Science and Environment (IJSE), 4(3), 79–90. https://doi.org/10.51601/ijse.v4i3.106

Issue

Section

Articles